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FO, Xenopus/Amphibian,D3 (5G9) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253087

FO, Xenopus/Amphibian,D3 (5G9) Antibody

Fo, Xenopus/Amphibian,D3 (Forkhead bo, Xenopus/Amphibian, protein D3) is a transcriptional regulator, a member of the Forkhead Bo, Xenopus/Amphibian, family. It is characterized by a winged-heli, Xenopus/Amphibian, DNA-binding structure and the important role it plays in embryonic development. Fo, Xenopus/Amphibian,D3 is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation. Fo, Xenopus/Amphibian,D3 is required for the maintenance of the mammalian neural crest; Fo, Xenopus/Amphibian,D3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures. Fo, Xenopus/Amphibian,D3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Fo, Xenopus/Amphibian,D3 is e, Xenopus/Amphibian,pressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues e, Xenopus/Amphibian,amined.

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SPECIFICATIONS

Catalog Number

253087

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human FO, Xenopus/Amphibian,D3 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q9UJU5

Clonality

5G9

Additional Info

Forkhead bo, Xenopus/Amphibian, protein D3; HNF3/FH transcription factor genesis; HFH2; FO, Xenopus/Amphibian,D3

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