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Formin Binding Protein 1 (FBP1, Formin Binding Protein 17, FBP17, FNBP1)

Formin Binding Protein 1 (FBP1, Formin Binding Protein 17, FBP17, FNBP1)

Cat no: F6002-62

Supplier: United States Biological
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The protein recognised by this antibody is a member of the formin binding protein family. The protein contains an N terminal Fer/Cdc42 interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled coil domain, a proline rich motif, a second coiled coil domain, a Rho family protein binding domain (RBD), and a C terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. Cellular Localization: Cytoplasmic Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F6002-62
Reactivities: Human, Mouse, Rat
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Kamioka Y et al. A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J Biol Chem 279:40091-9 (2004).
Additional info: Species Crossreactivity: Reacts with Human. Predicted to react with Mouse and Rat due to sequence homology.

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