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FOXO4 (FOXO4 (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, AFX, AFX1, MLLT7)

FOXO4 (FOXO4 (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, AFX, AFX1, MLLT7)

Cat no: F9049-45D

Supplier: United States Biological
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FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F9049-45D
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, 0.1% sodium azide.
P type: Pab
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human FOXO4.

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