FOXP1 (Forkhead Box P1, 12CC4, 3110052D19Rik, 4932443N09Rik, AI461938, AW494214, FLJ23741, hFKH1B, Glutamine Rich Factor 1, HSPC215, MGC12942, MGC88572, MGC99551, QRF1)

FOXP1, an 85kD member of the winged helix/forkhead transcription factor family. The FOXP1 transcription factor is widely expressed in human tissues and is predominantly localised to the nucleus. However, the level of expression does vary between cells and between different tissues. The expression of FOXP1 is reported to be abnormal in a range of solid tumors. Studies suggest that FOXP1 functions as a transcriptional repressor.\n\nApplications:\nSuitable for use in Immunohistochemistry (frozen and paraffin). Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (paraffin): 1:200-1:500 requires antigen retrieval using heat treatment prior to staining of paraffin sections.\n1mM EDTA pH8.0 is recommended for this purpose.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F9049-98C

Size

100ug

Applications

IHC

Hosts

Mouse

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2a

References

1. Banham, A.H. et al. (2005) Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma. Clin. Cancer Res.11:1065

Additional Info

Recognizes human FOXP1. Species crossreactivity: mouse

Alternative Names

Forkhead Box Protein P1