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FOXP1 (Forkhead Box Protein P1, HSPC215)

Cat no: F9049-98G

FOXP1 (Forkhead Box Protein P1, HSPC215)

Recognises human FOXP1, an 85kD member of the winged helix/forkhead transcription factor family. The FOXP1 transcription factor is widely expressed in human tissues and is predominantly localised to the nucleus. However, the level of expression does vary between cells and between different tissues. The expression of FOXP1 is reported to be abnormal in a range of solid tumours. Studies suggest that FOXP1 functions as a transcriptional repressor. The antibody produced by this clone does not recognize closely related molecules FOXP2, FOXP3 or FOXP4. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Western blotting: Detects a band of approximately 85kD in Tonsil extracts.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml\nImmunohistochemistry: Frozen\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F9049-98G

Size

50ug

Applications

IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes human FOXP1. Species sequence homology: mouse.

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