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FOXP3 (Forkhead Box P3, AIID, DIETER, IPEX, JM2, MGC141961, MGC141963, PIDX, SCURFIN, XPID) (Alexa Fluor(R)647)

Cat no: F9050-11A2

FOXP3 (Forkhead Box P3, AIID, DIETER, IPEX, JM2, MGC141961, MGC141963, PIDX, SCURFIN, XPID) (Alexa Fluor(R)647)

FoxP3 is a 48kD forkhead transcription factor family member, which was originally identified as the novel protein scurfin. FoxP3 functions as a DNA binding protein that represses transcription, and is reported to be involved in the regulation of T cell activation, differentiation and homeostasis. FoxP3 is primarily expressed within the nuclei of CD25+/CD4+ regulatory T cells (Tr). This population of FoxP3+/CD25+/CD4+ Tr cells plays an essential role in controlling autoimmunity and the immunopathology of human diseases.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilutions:\nFlow Cytometry: Neat; 20ul labels 10e5-10e8 cells in 100ul\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4 degrees C. Freezing Alexa Fluor(R) conjugates will result in a substantial loss of activity. AlexaFluor(R) conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

F9050-11A2

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Labeled with Alexa Fluor(R)647.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Alvaro, T. et al. (2005) Outcome in Hodgkin

Additional Info

Recognizes human FoxP3.

Alternative Names

Forkhead Box Protein P3

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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