FPR1 (I207) Peptide

Cat no: BS5719P

Supplier: Bioworld Technology, Inc.

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The N-formyl peptide receptor (FPR) is a chemotactic G protein-coupled receptor (GPCR) that is found on the surface of phagocytic leukocytes, such as neutrophils and monocytes. The human FPR family comprises three members, FPR, FPRL1 (also designated lipoxin A4 receptor) and FPRL2, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR, a seven transmembrane-domain receptor, primarily binds the chemoattractant N-formyl-methionyl-leucyl-phenylalanine (fMLP), which activates several biological processes, including chemotaxis, transcriptional activation, and actin reorganization. FPR also mediates the inhibition of neutrophil migration through binding to specific peptide fragments of annexin I, which causes calcium transients and affects inflammatory responses.

Catalogue number:	BS5719P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P21462
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide FPR1 (I207). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; Short name=FPR; N-formylpeptide chemoattractant receptor
Additional info:	This peptide can be used with studies using BS5719 FPR1 (I207) pAb.

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FPR1 (I207) Peptide

Cat no: BS5719P

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