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Fractin Antibody

Fractin Antibody

Cat no: 253137

Supplier: ABBIOTEC
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During apoptosis, beta actin is cleaved by activated caspase 3 between Asp244 and Gly245. This cleavage results in the release of an appro, Xenopus/Amphibian,imately 130 amino acid (15 kDa) fragment from the C-terminus of beta actin and a 32 kDa (244 amino acid) N-terminal fragment of actin, known as fractin. The C -terminus of the fractin fragment represents an apoptosis-specific neoepitope that is not antigenic in native full-length beta actin and therefore presents a novel and specific marker for distinguishing apoptotic from necrotic cells.
Catalogue number: 253137
Reactivities: Human, Rabbit
Applications: Immunohistochemistry
Size: 0.1 ml
Accession: P60709
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human fractin.
Format: Each vial contains 0.1 ml of crude serum.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Actin, cytoplasmic 1; Beta-actin; ACTB
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