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Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1, Fragile X Mental Retardation Syndrome-related Protein 1, Fragile X Mental Retardation-related Protein 1, hFXR1p)

Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1, Fragile X Mental Retardation Syndrome-related Protein 1, Fragile X Mental Retardation-related Protein 1, hFXR1p)

Cat no: F6072-20

Supplier: United States Biological
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The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. Positive Control: NIH/3T3 cell lysate
Catalogue number: F6072-20
Reactivities: Human
Hosts: Goat
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Coon H, Matsunami N, Stevens J, Miller J, Pingree C, Camp NJ, Thomas A, Krasny L, Lainhart J, Leppert MF, McMahon W. Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree. Hum Hered. 2005;60(4):220-6. Epub 2006 Jan 2. PMID: 16391490
Additional info: Species Crossreactivity: Human. Other species not tested.

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