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Frizzled 3 (Frizzled Family Receptor 3, Frizzled-3, FZD3, Fz-3, FZD3, hFz3)

Cat no: F6401-11H

Frizzled 3 (Frizzled Family Receptor 3, Frizzled-3, FZD3, Fz-3, FZD3, hFz3)

Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling. It is widely expressed, mostly in brain and urogenital tissues. FZD3 is also expressed in the epidermis and developing hair follicles. FZD3 has been implicated in the development of axon tracts in the forebrain. A truncated form of FZD3 exists due to alternative splicing. FZD3 expression has been documented in blood, brain, colon, kidney, lung, lymph node, ovary, pancreas, skeletal muscle, skin, spinal cord, stomach, urogenital tract, and uterus. ESTs have been isolated from amnion, brain, colon, eye, heart, kidney, lymph, skin, and testis libraries.\n\nApplications:\nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (paraffin): 11ug/ml\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHuman Brain, Neurons and Glia\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F6401-11H

Size

50ug

Applications

IHC

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes human FZD3. Species Crossreactivity: mouse and rat.

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