Home  >  Products  >  Frizzled 7 (Frizzled Family Receptor 7, Frizzled-7, Fz-7, FZD7, hFz7, FzE3)
Frizzled 7 (Frizzled Family Receptor 7, Frizzled-7, Fz-7, FZD7, hFz7, FzE3)

Frizzled 7 (Frizzled Family Receptor 7, Frizzled-7, Fz-7, FZD7, hFz7, FzE3)

Cat no: F6401-30J

Supplier: United States Biological
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FZD7, a Frizzled Receptor, is a receptor for Wnt signaling proteins. FZD7 downregulates the functions of the tumor suppressor gene APC and thereby enhances beta catenin-mediated signals. FZD7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 20ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Heart, Cardiac myocytes Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F6401-30J
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Sagara N et.al Biochem Biophys Res Commun., 252(1):117-22 (1998 Nov 9) 2. Tanaka et.al PNAS 95 (17); 10164-10169 (August 18, 1998) 3. Kirikoshi H et.al Int J Oncol., 19(1):111-5 (2001 Jul)
Additional info: Recognizes human FZD7.

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