FSTL1 BioAssay(TM) ELISA Kit, Human

Supplier:

United States Biological

Cat no: 143841

FSTL1 BioAssay(TM) ELISA Kit, Human

Sandwich ELISA quantitative detection kit for Human FSTL1 in cell culture supernates, serum and plasma (heparin, EDTA).\n\nFollistatin-related protein 1, also called FSTL1 or FRP is a protein that in humans is encoded by the FSTL1 gene. FSTL1 gene is mapped to chromosome 3q13.33 based on an alignment of FSTL1 sequence with the genomic sequence (GRCh37). This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. This gene may modulate the action of some growth factors on cell proliferation and differentiation. It was suggested that fibroblast-secreted FSTL1 acts on macrophages to increase TNF and IL1B production and IL6 activity.\n\nAssay Range:\n312pg/ml-20,000pg/ml\n\nSensitivity:\n< 10 pg/ml\n\nCrossreactivity:\nThere is no detectable cross-reactivity with other relevant proteins.\n\nUniprot ID:\nQ12841 \n\nEntrez Gene ID:\n11167\n\nKit Components:\n96-well plate pre-coated with anti-FSTL1, Human\nLyophilized recombinant FSTL1, Human standard, 10ng/tube, 2Ea\nUSB Cat No Kit Component\n143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)\n143697 Sample diluent buffer, 30ml\n143698 Antibody diluent buffer, 12ml\n143699 ABC diluent buffer, 12ml\n143700 TMB color developing agent, 10ml\n143701 TMB stop solution, 10ml\n\nStorage and Handling:\nStore at 4 degrees C for 6 months, at -20 degrees C for 12 months. Avoid multiple freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

143841

Size

96Tests

References

1. Sundaram, G. M., Common, J. E. A., Gopal, F. E., Srikanta, S., Lakshman, K., Lunny, D. P., Lim, T. C., Tanavde, V., Lane, E. B., Sampath, P. 'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing. Nature 495: 103-106, 2013.\n2. Ye, L., Li, S., Ye, D., Yang, D., Yue, F., Guo, Y., Chen, X., Chen, F., Zhang, J., Song, X.Livin expression may be regulated by miR-198 in human prostate cancer cell lines. Europ. J. Cancer 49: 734-740, 2013.\n

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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