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FTL (Ferritin, Light Polypeptide, MGC71996, L apoferritin, Ferritin light polypeptide-like 3)

FTL (Ferritin, Light Polypeptide, MGC71996, L apoferritin, Ferritin light polypeptide-like 3)

Cat no: F4015-13B

Supplier: United States Biological
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FTL is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:4000 Sandwich ELISA: 1-2ug/ml. Western Blot: 0.1-0.3ug/ml. Band observed at ~20kD in human brain (Cerebellum), liver and placenta lysates. Immunohistochemistry (Paraffin): 3-6ug/ml shows cytoplasm staining of pyramydal neurons in human brain cortex. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F4015-13B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: FTL; ferritin, light polypeptide; MGC71996; L apoferritin; ferritin L subunit; ferritin L-chain; ferritin light chain; ferritin light polypeptide-like 3
References: 1. Sammarco MC, Ditch S, Banerjee A, Grabczyk E.Ferritin L and H subunits are differentially regulated on a post-transcriptional level. J. Biol. Chem. 2008 Feb 283 (8): 4578-87. PMID: 18160403
Additional info: Recognizes human FTL. Species Sequence Homology: mouse, rat, canine and bovine.

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