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FUZ (Protein Fuzzy Homolog, FY)

Cat no: F9600-50

FUZ (Protein Fuzzy Homolog, FY)

FUZ is the human homolog of Drosophila fy protein and belongs to the fuzzy family. The fy gene of Drosophila encodes a novel four-pass transmembrane protein that plays two roles in the development of hairs on the Drosophila wing. The first is to specify the correct orientation of the hair by restricting its initiation to the distal vertex of the cell. The second role is to permit the development of just a single cell hair by maintaining the integrity of the F-actin and microtubule arrays that are required for hair development. In humans, the protein is involved in cytoskeleton function and cell polarity in epithelial cells. The human fuz gene is localized on chromosome 19q13.33.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 2-6ug/ml\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHuman, mouse and rat lung lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F9600-50

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

References

1. Ota, T. et al. Nat. Genet. 36:40-45 (2004).

Additional Info

Recognizes human FUZ. Species Crossreactivity: chimpanzee, mouse, rat. Species sequence homology: canine.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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