FXY2 (MID2, Midline 2, Midin-2, Midline Defect 2, RING Finger Protein 60, Tripartite Motif-containing Protein 1, Tripartite Motif Protein 1, TRIM1)

MID2 is a member of the tripartite motif (TRIM) family. The MID motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Its function has not been identified. Alternate splicing of the gene encoding MID2 results in two transcript variants encoding different isoforms.\n\nCellular Localization: Cytoplasmic\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F9400-02

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Mouse, NHP

Form

Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Buchner G et al. MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. Hum Mol Genet 8:1397-407 (1999). <PUBMED:10400986>

Additional Info

Species Crossreactivity: Expected to crossreact with Human, Mouse (92% identity with immunogen) and Monkey (100% identity with immunogen) due to sequence homology.