FZD8 (Frizzled 8, Frizzled-8, Fz-8, hFz8)

Cat no: F6401-38D

Supplier: United States Biological

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Additional Information

Frizzled 8 is one of the mammalian homologs of the Drosophila frizzled proteins, which are known to interact with Wnt proteins (1 and 2). Frizzled 8, originally isolated from a human fetal cDNA library, is also known also asFZD8 or FZ8. Applications: Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Immunohistochemistry (paraffin): 3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Pancreas lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	F6401-38D
Reactivities:	Human
Hosts:	Goat
Applications:	Immunohistochemistry, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Keay SK, Szekely Z, Conrads TP, Veenstra TD, Barchi JJ Jr, Zhang CO, Koch KR, Michejda CJ. An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide. Proc Natl Acad Sci USA. 2004 Aug 10;101(32):11803-8. Epub 2004 Jul 28. PMID: 15282374.
Additional info:	Recognizes human FZD8. Species sequence homology: mouse, rat, canine.

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FZD8 (Frizzled 8, Frizzled-8, Fz-8, hFz8)

Cat no: F6401-38D

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