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G Protein Coupled Receptor 105 (GPR105, KIAA0001, P2Y Purinoceptor 14, P2RY14, P2Y14, UDP-glucose Receptor)

G Protein Coupled Receptor 105 (GPR105, KIAA0001, P2Y Purinoceptor 14, P2RY14, P2Y14, UDP-glucose Receptor)

Cat no: G8601-09F

Supplier: United States Biological
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GPR105 is a Sugar-Sensing Receptor. GPR105 is a G-protein-coupled receptor identifying a quiescent, primitive population of hematopoietic cells restricted to bone marrow. GPC105 has been suggested to mediates primitive cell responses to specific hematopoietic microenvironments and extends the known immune system functions of P2Y receptors to the stem cell level. GPR105 has also been suggested to play an important role in peripheral and neuroimmune function in response to extracellular UDP-sugars. GPR105 has been reported to be expressed in brain. ESTs have been isolated from kidney, placenta, uterus, and heart/melanocyte/uterus libraries. Applications: Suitable for use in Immunofluorescence, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 4ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human transfection-cells expressing vector only Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8601-09F
Reactivities: Human
Hosts: Rabbit
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: G-protein Coupled Receptor 105, Purinergic Receptor P2Y, G-protein Coupled, 14
Additional info: Recognizes human GPR105.

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