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G Protein Coupled Receptor 15 (GPR15, Brother of Bonzo, BoB, MGC126828, MGC126830)

G Protein Coupled Receptor 15 (GPR15, Brother of Bonzo, BoB, MGC126828, MGC126830)

Cat no: G8600-19F

Supplier: United States Biological
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G protein-coupled receptor GPR15 is an Orphan-A GPCR with an unknown ligand. Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use BOB/GPR15 for productive infection, suggesting that this cofactor may play a role in HIV-1 pathogenesis and transmission. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 10ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human kidney Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8600-19F
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: G Protein-coupled Receptor 15, G-protein Coupled Receptor 15
Additional info: Recognizes human GPR15.

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