GPR85, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. The rat counterpart of SREB2 is involved in the development of the cerebral cortex. GPR85 has been reported to be expressed in several areas of human and rat CNS (Matsumoto et al., 2000), as well as in genital organs. ESTs have been isolated from B-cell/lung/testis, brain, testis, and embryo libraries, as well as many mouse tissue libraries.
Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (paraffin): 10-19ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control:
Human putamen, neurons
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.