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GABA A Receptor Associated Protein (GABARAP)

GABA A Receptor Associated Protein (GABARAP)

Cat no: G1015-27C

Supplier: United States Biological
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Gamma-aminobutyric acid A receptors are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP [GABA(A) receptor-associated protein] is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. It clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-10,000 Immunohistochemistry (Paraffin): 1:500-1000 Immunocytochemistry: 1:100-250 Optimal dilutions to be determined by the researcher. Positive Control: Western Blot: Fetal kidney, SH-SY5Y, HepG2, and fetal brain lysates Immunohistochemistry: Human brain tissue Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: G1015-27C
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM tris-glycine, pH7.4, 0.15M NaCl, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Purity: Supernatant
References: 1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
Additional info: Recognizes human GABARAP at~17kD. Species Crossreactivity: mouse, rat.

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