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GABA A receptor gamma 2 subunit

Cat no: G1015-20R

GABA A receptor gamma 2 subunit

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.\n\nApplications: \nSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nImmunoprecipitation: 15ug/100ug cell lysate\nWestern Blot: 1:1000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

G1015-20R

Size

100ul

Applications

IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov

Form

Supplied as a liquid in 10mM HEPES, pH 7.5, containing 150mM NaCl, 100ug/ml BSA, and 50% glycerol.

P Type

Pab

Purity

Purified by affinity chromatography.

References

1. Tretter, V., et al, Stoichiometry and assembly of a recombinant GABA-A receptor subtype. J. Neurosci., 17: 2728-37, 1997

Additional Info

Reacts with the 44-46kD gamma 2 subunit of rat brain GABA-A. There is no known reactivity with other GABA subunits. Species Crossreactivity mouse, human and bovine.

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