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GABA A receptor gamma 2 subunit

GABA A receptor gamma 2 subunit

Cat no: G1015-20R

Supplier: United States Biological
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GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Immunoprecipitation: 15ug/100ug cell lysate Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G1015-20R
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 10mM HEPES, pH 7.5, containing 150mM NaCl, 100ug/ml BSA, and 50% glycerol.
P type: Pab
Purity: Purified by affinity chromatography.
References: 1. Tretter, V., et al, Stoichiometry and assembly of a recombinant GABA-A receptor subtype. J. Neurosci., 17: 2728-37, 1997
Additional info: Reacts with the 44-46kD gamma 2 subunit of rat brain GABA-A. There is no known reactivity with other GABA subunits. Species Crossreactivity mouse, human and bovine.

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