Home  >  Products  >  GABABR1 (Ser923) Antibody
GABABR1 (Ser923) Antibody

GABABR1 (Ser923) Antibody

Cat no: 252545

Supplier: ABBIOTEC
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Gamma-aminobutyric acid type B receptor subunit 1 (GABA-Receptor, R-1 subunit), together with the GABA-Receptor, R-2 subunit, forms a receptor for GABA. The activity of GABA-B-Receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulate phospholipase A2, activates potassium channels, inactivate voltage-dependent calcium-channels and modulate inositol phospholipids hydrolysis. The GABA-B-Receptor plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-Receptors inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal e, Xenopus/Amphibian,citability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. The GABA receptor has not only been implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep,Mouse,uscle rela, Xenopus/Amphibian,ation and antinociception. Phosphorylation of Ser923 is important in the regulation of GABAB receptor function.
Catalogue number: 252545
Reactivities: Human, Mouse, Bovine, Rabbit
Applications: Western Blot
Size: 0.1 ml
Accession: Q9Z0U4
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser923 of rat GABAB receptor, R1-subunit.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type: Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype: Rabbit IgG
Additional info: Gamma-aminobutyric acid type B receptor subunit 1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1; Gabbr1
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave