Home  >  Products  >  Galectin-3 (GAL3, Carbohydrate Binding Protein 35, CBP35, Galactose Specific Lectin 3, Galactoside Binding Protein, GALBP, IgE Binding Protein, Laminin Binding Protein, Lectin Galactose Binding Soluble 3, LGALS3, MAC2)
Galectin-3 (GAL3, Carbohydrate Binding Protein 35, CBP35, Galactose Specific Lectin 3, Galactoside Binding Protein, GALBP, IgE Binding Protein, Laminin Binding Protein, Lectin Galactose Binding Soluble 3, LGALS3, MAC2)

Galectin-3 (GAL3, Carbohydrate Binding Protein 35, CBP35, Galactose Specific Lectin 3, Galactoside Binding Protein, GALBP, IgE Binding Protein, Laminin Binding Protein, Lectin Galactose Binding Soluble 3, LGALS3, MAC2)

Cat no: G1044-53C

Supplier: United States Biological
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Galectins are a family of beta-galactoside-binding animal lectins that are associated with diverse cellular events, including immune response. Glectin-3 has previously been identified in rat, mouse and human tissues and is evolutionarily highly conserved. It is an abundant cell-surface component of inflammatory macrophages and their major non-integrin laminin-binding protein. It is also mainly expressed in colonic epithelial cells. Galectin-3 is a cell surface receptor of the advanced glycosylation end products (AGE), which has involvement in the pathogenesis of nephropathy and other diabetic complications (1-2). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:5000-10,000 Immunohistochemistry: 1:2,000-5,000 Immunocytochemistry: 1:100-250 Flow Cytometry: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: G1044-53C
Reactivities: Human
Hosts: Rabbit
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Henderson NC, et al. Proc Natl Acad Sci 103(13):5060-5, 2006 2. Lacobini C, et al. J Am Soc Nephrol 14:S264-S270, 2003
Additional info: Recognizes human Galectin-3.

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