Galectin-9 BioAssay(TM) ELISA Kit, Human

Sandwich ELISA quantitative detection kit for Human Galectin-9 in cell culture supernates, serum and plasma (heparin, EDTA).\n\nGalectin-9, also called HUAT or LGALS9A is a protein that in humans is encoded by the LGALS9 gene. This gene is mapped to 17q11.2. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. The protein has N- and C- terminal carbohydrate-binding domains connected by a link peptide.\n\nAssay Range:\n93.8pg/ml-6000pg/ml\n\nSensitivity:\n< 10 pg/ml\n\nCrossreactivity:\nThere is no detectable cross-reactivity with other relevant proteins.\n\nUniprot ID:\nO00182\n\nEntrez Gene ID:\n3965\n\nKit Components:\n96-well plate pre-coated with anti-Galectin-9, Human\nLyophilized recombinant Galectin-9, Human standard, 10ng/tube, 2Ea\nUSB Cat No Kit Component\n143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)\n143697 Sample diluent buffer, 30ml\n143698 Antibody diluent buffer, 12ml\n143699 ABC diluent buffer, 12ml\n143700 TMB color developing agent, 10ml\n143701 TMB stop solution, 10ml\n\nStorage and Handling:\nStore at 4 degrees C for 6 months, at -20 degrees C for 12 months. Avoid multiple freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

143848

Size

96Tests

References

1. Matsumoto, R., Matsumoto, H., Seki, M., Hata, M., Asano, Y., Kanegasaki, S., Stevens, R. L., Hirashima, M. Human ecalectin, a variant of human galectin-9 , is a novel eosinophil chemoattractant produced by T lymphocytes. J. Biol. Chem. 273: 16976-16984, 1998.\n2. Tureci, O., Schmitt, H., Fadle, N., Pfreundschuh, M, Sahin, U. Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. J. Biol. Chem. 272: 6416-6422, 1997.\n3. Wada, J., Kanwar, Y. S. Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin. J. Biol. Chem. 272: 6078-6086, 1997.\n