Ganglioside GM1, Human (Monosialoganglioside

Supplier:

United States Biological

Cat no: G2004-92

Ganglioside GM1, Human (Monosialoganglioside

A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system. It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorylation and synaptic function.\n\nApplications:\nUseful as an antigen and receptor for a cholera toxin, growth inhibitor marker in fibroblasts and marker for lymphoid subpopulations. Stable for the majority of sialidase.\n\nRecommended Dilutions: \nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O or in chloroform:methanol 2:1. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

G2004-92

Size

1mg

Form

Supplied as a lyophilized powder from a water solution. Reconstitute with sterile ddH2O up to 20mg/ml (to form micelles) or in chloroform:methanol 2:1 at 1mg/ml.

Purity

(same/more than)98% pure (HPTLC). Purified by repeated HPLC.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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