Quick Search
Products GANT61 (NSC 136476, 2,2'-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine)
| Catalogue number: | 044837 |
| Size: | 1mg |
| Purity: | >98% |
| Alternative names: | NSC 136476, 2,2'-((Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl)bis(methylene))bis(N,N-dimethyl)-benzenamine |
| References: | Product Reference: ?Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists: M. Lauth, et al.; PNAS 104, 8455 (2007) ?Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells: P. Desch, et al.; Oncogene 29, 4885 (2010) ?Hedgehog signaling drives cellular survival in human colon carcinoma cells: T. Mazumdar, et al.; Cancer Res. 71, 1092 (2011) ?HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma. M. Yan, et al.; Oral Oncol. 47, 504 (2011) ?Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells: T. Mazumdar, et al.; Cancer Res. (Epub ahead of print) (2011) ? |
Get the Best Promotions
