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GARP (Leucine-rich Repeat-containing Protein 32, Garpin, Glycoprotein A Repetitions Predominant, LRRC32, D11S833E)

GARP (Leucine-rich Repeat-containing Protein 32, Garpin, Glycoprotein A Repetitions Predominant, LRRC32, D11S833E)

Cat no: G2013-70B

Supplier: United States Biological
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GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2013-70B
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Rabbit
Applications: Flow Cytometry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
References: 1. Ollendorff, V. et al. Cell Growth Differ. 5:213-219 (1994). 2. Wang, R. et al. PLoS ONE. 3(7):e2705 (2008). 3. Ollendorff, V. et al. Mammalian Genome. 2:195-200 (1992).
Additional info: Recognizes human GARP. Species Crossreactivity: monkey, mouse, rat. Species sequence homology: canine.

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