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Gastric Inhibitory Peptide (GIP)

Cat no: G2019-02

Gastric Inhibitory Peptide (GIP)

Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C-terminal octapeptide. The glucagon precursor contains at least 3 intervening sequences that divide the protein-coding portion into 4 regions corresponding to the signal peptide and part of the N-terminal peptide, the remainder of the N-terminal peptide and glucagon, glucagon-like peptide-1 (GLP1), and GLP2. GIP, Gastric inhibitory polypeptide, also known as glucose-dependent insulinotropic polypeptide (GIP), is a 42-amino acid hormone (chr 17q21.3) that stimulates insulin secretion in the presence of glucose. GIP is derived by proteolytic processing of a 153-residue precursor, preproGIP; it is a member of a family of structurally related hormones that includes secretin, glucagon, vasoactive intestinal peptide, and growth hormone-releasing factor.\n\nApplications:\nSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. \n\nRecommended Dilutions:\nWestern Blot: 1-10ug/ml using Chemiluminescence technique.\nELISA:

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SPECIFICATIONS

Catalog Number

G2019-02

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Meier JJ et al, (2003) Regulatory peptides, 95-100. 2. Inagaki N et al, (1989) Mol Endocrinology 1014-21.

Additional Info

Recognizes human Gastric Inhibitory Peptide.

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