GAT-3 Antibody

Cat no: 253159

Supplier: ABBIOTEC

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Description
Additional Information

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a chloride channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis.

Catalogue number:	253159
Reactivities:	Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P31647
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABA transporter (GAT) 3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11; Slc6a11