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GATA-2 (GATA binding protein 2, Endothelial transcription factor GATA-2, FLJ45948, MGC2306, NFE1B)

GATA-2 (GATA binding protein 2, Endothelial transcription factor GATA-2, FLJ45948, MGC2306, NFE1B)

Cat no: G2021-40B

Supplier: United States Biological
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GATA factors constitute a family of transcriptional regulatory factors that bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. GATA-1/2/3 are each expressed in the hematopoietic system while GATA 4/5/6 are each expressed in the developing heart and in gastrointestinal and gut-derived tissues. Specifically, GATA-2 is expressed in hematopoietic progenitors and stem cells. GATA-2 expression is associated with cell proliferation. GATA-2 is 480 amino acids in length and contains 2 Zn finger domains responsible for DNA binding (aa 295-319 and 349-373). Over aa 15-279 human GATA-2 share 96% identity with mouse GATA-2. Applications: Suitable for Western Blot. Other applications not tested. Storage: Lyophilized samples are stable for twelve months from date of receipt when stored at -20 degrees C to -70 degrees C. Upon reconstitution, the antibody can be stored at 2 degrees -8 degrees C for 1 month without detectable loss of activity. Reconstituted antibody can also be aliquotted and stored frozen at -20 degrees C to -70 degrees C in a manual defrost freezer for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Catalogue number: G2021-40B
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Lyophilized from a 0.2um sterile-filtered solution in PBS with 5% trehalose.
P type: Mab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
Additional info: The antibody detects endogenous human/mouse GATA-2 on Western blots with an approximate molecular weight of 58 kDa.

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