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GATA-2 (GATA binding protein 2, Endothelial transcription factor GATA-2, FLJ45948, MGC2306, NFE1B)

Cat no: G2021-40B

GATA-2 (GATA binding protein 2, Endothelial transcription factor GATA-2, FLJ45948, MGC2306, NFE1B)

GATA factors constitute a family of transcriptional regulatory factors that bind to the consensus \nDNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression \nand morphogenesis. GATA-1/2/3 are each expressed in the hematopoietic system while \nGATA 4/5/6 are each expressed in the developing heart and in gastrointestinal and gut-derived \ntissues. Specifically, GATA-2 is expressed in hematopoietic progenitors and stem cells. GATA-2 \nexpression is associated with cell proliferation. GATA-2 is 480 amino acids in length and \ncontains 2 Zn finger domains responsible for DNA binding (aa 295-319 and 349-373). Over \naa 15-279 human GATA-2 share 96% identity with mouse GATA-2. \n\nApplications:\nSuitable for Western Blot. Other applications not tested.\n\nStorage:\nLyophilized samples are stable for twelve months from date of receipt when stored at -20 degrees C to -70 degrees C. Upon reconstitution, the antibody can be stored at 2 degrees -8 degrees C for 1 month without detectable loss of activity. Reconstituted antibody can also be aliquotted and stored frozen at -20 degrees C to -70 degrees C in a manual defrost freezer for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

G2021-40B

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum

Form

Lyophilized from a 0.2um sterile-filtered solution in PBS with 5% trehalose.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

Additional Info

The antibody detects endogenous human/mouse GATA-2 on Western blots with an approximate molecular weight of 58 kDa.

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