The GATA family of erythroid transcription factors is categorized by the ability to bind to the consensus sequence GATA. GATA transcription factors play important roles in the development of many organ systems, including hematopoietic, cardiovascular, reproductive, and gut-endoderm derived tissue. GATA transcription factor homologs in zebrafish are highly conserved in sequence, expression pattern, and function, making the zebrafish an appropriate model for the study of GATA factors. Gata-2a in zebrafish is essential to hematopoiesis and is dynamically expressed in the central nervous system and hematopoietic tissues. Activation of Gata-2 in zebrafish is dependent on the bone morphogenetic protein signaling pathway.
Applications:
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:
ELISA: 1:5000-1:20,000
Optimal dilutions to be determined by the researcher.
Control Peptide: G2021-42P
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.