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GATA-4 (GATA4, Transcription Factor GATA-4, GATA-binding Factor 4)

GATA-4 (GATA4, Transcription Factor GATA-4, GATA-binding Factor 4)

Cat no: G2021-51F

Supplier: United States Biological
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Transcription factor GATA-4 is one of the zinc-finger transcription protein factor in mammals encoded by the GATA4 gene. This is a protein thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. It is expressed in early mesenchymal differentiation paradigms as well. GATA-4 plays a critical role in regulating basal or stress induced gene expression in cardiac and smooth muscle cell types. Mutations in the GATA4 gene have been associated with cardiac septal defects. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human kidney Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2021-51F
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Garg, V. et al. Nature 424:443-447 (2003). 2. Durocher, D. et al. EMBO. J. 16:5687-5696 (1997). 3. White, R.A. et al. Genomics 27:20
Additional info: Recognizes human GATA-4. Species sequence homology: mouse, rat, monkey, canine, rhesus monkey.

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