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Gata-6, ID (Zinc Finger Transcription Factor Gata6, gata6)

Gata-6, ID (Zinc Finger Transcription Factor Gata6, gata6)

Cat no: G2021-56M

Supplier: United States Biological
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The GATA family of erythroid transcription factors is categorized by the ability to bind to the consensus sequence GATA. GATA transcription factors play important roles in the development of many organ systems, including hematopoietic, cardiovascular, reproductive, and gut-endoderm derived tissue. GATA transcription factor homologs in zebrafish are highly conserved in sequence, expression pattern, and function, making the zebrafish an appropriate model for the study of GATA factors. Presence of Gata-6 in the cardiac mesoderm of zebrafish was shown to be essential to cardiogenesis, where the prevailing theory was that zebrafish did not require an endoderm for heart formation. Gata-5 and Gata-6 have also been shown to be redundant for cardiomyocyte specification. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: G2021-56P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2021-56M
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Heicklen-Klein, A et al (2005) Sem. Cell Dev. Biol. 16(1):95-106. 2. Peterkin, T et al (2003) EMBO J. 22(16):4260-4273. 3. Holtzinger, A and Evans, T (2007) Dev. Biol. 312(2):613-622.
Additional info: Recognizes zebrafish Gata-6.

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