Home  >  Products  >  GCDFP15 (Prolactin-inducible Protein, Gross Cystic Disease Fluid Protein 15, GCDFP-15, Prolactin-induced Protein, Secretory Actin-binding Protein, SABP, gp17, PIP, GPIP4)
GCDFP15 (Prolactin-inducible Protein, Gross Cystic Disease Fluid Protein 15, GCDFP-15, Prolactin-induced Protein, Secretory Actin-binding Protein, SABP, gp17, PIP, GPIP4)

GCDFP15 (Prolactin-inducible Protein, Gross Cystic Disease Fluid Protein 15, GCDFP-15, Prolactin-induced Protein, Secretory Actin-binding Protein, SABP, gp17, PIP, GPIP4)

Cat no: G2023-26F

Supplier: United States Biological
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Human breast gross cystic disease is a common benign breast disease which occurs most frequently in the age range of 40-50 years, then becomes very infrequent after menopause. It is characterized by production of a unique fluid secretion which accumulates in the breast cysts composed of several glycoproteins, including a unique 15kD monomer protein, GCDFP-15. The protein is present in normal apocrine epithelium, metaplastic apocrine epithelium of the breast, and breast carcinomas with apocrine features. The protein is regarded as a specific functional marker of apocrine cells. It is expressed during fetal development and may represent a common marker of embryologically linked glandular structures. The gene coding for GCDFP-15 is localized in the long arm of chromosome 7. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: >1:128,000 Western Blot: 0.3-1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: A431 cell lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2023-26F
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. O'Connell FP, Wang HH, Odze RD. Utility of immunohistochemistry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract. Arch Pathol Lab Med. 2005 Mar;129(3):338-47. PMID: 15737028.
Additional info: Recognizes human GCDFP15.

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