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GDF-7, Recombinant, Human (Growth/Differentiation Factor-7, BMP-12)

Cat no: 143346

GDF-7, Recombinant, Human (Growth/Differentiation Factor-7, BMP-12)

GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors.It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue.Recombinant human GDF-7 is a 28kD disulfide linked homodimer containing two 129 amino acid residues.\n\nBiological Activity:\nDetermined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.\n\nAA Sequence:\nTALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR\n\nQuality Control:\nVerified by N-terminal and Mass Spectrometry analyses (when applicable).\n\nEndotoxin:\n<0.1ng/ug of protein (<1EU/ug).\n\nProtein Content:\nVerified by UV Spectroscopy and/or SDS-PAGE gel.\n\nStorage and Stability:\nStore lyophilized products at -20 degrees C. For reconstituted solutions of most products, we recommend short-term storage at 4 degrees C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20 degrees C. Additional freeze/thaw cycles may cause some denaturation of the protein.

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SPECIFICATIONS

Catalog Number

143346

Size

2ug

Form

Supplied as a lyophilized powder.

Purity

(same/more than)98% by SDS-PAGE gel and HPLC analyses.

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