Home  >  Products  >  Gelsolin (Actin depolymerizing factor, ADF, AGEL, Amyloidosis Finnish type, Brevin, DKFZp313L0718, GSN, Calcium regulated actin binding protein)
Gelsolin (Actin depolymerizing factor, ADF, AGEL, Amyloidosis Finnish type, Brevin, DKFZp313L0718, GSN, Calcium regulated actin binding protein)

Gelsolin (Actin depolymerizing factor, ADF, AGEL, Amyloidosis Finnish type, Brevin, DKFZp313L0718, GSN, Calcium regulated actin binding protein)

Cat no: G2024-52A

Supplier: United States Biological
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Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions. Cellular Localization: Cytoplasmic and Secreted Applications: Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G2024-52A
Reactivities: Human, Bovine, Porcine, Rabbit
Hosts: Mouse
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Size: 100ul
Form: As reported
P type: Mab
Isotype: IgG1
Purity: Ascites
Alternative names: Actin depolymerizing factor, ADF, AGEL, Amyloidosis Finnish type, Brevin, DKFZp313L0718, GSN
Additional info: Species Crossreactivity: Crossreacts with Human, bovine, porcine and Rabbit.

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