GFAP, Blocking Protein (Glial Fibrillary Acidic Protein)

Supplier:

United States Biological

Cat no: 136900

GFAP, Blocking Protein (Glial Fibrillary Acidic Protein)

Blocking Protein for G2032-27J.\n\nHuman GFAP is a 49.7kD protein (432aa) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies. Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP.\n\nSource:\nPurified Bovine GFAP protein\n\nAA Sequence:\nMERRRVTSATRRSYVSSSEMVVGGRRLGPG TRLSLARMPP PLPARVDFSLAGALNSGFKETRASERAEMM ELNDRFASYI EKVRFLEQQN KALAAELNQLRAKEPTKLAD VYQAELRELR LRLDQLTANS ARLEVERDNL AQDLGTLRQK LQDETNQRLE AENNLAAYRQ EADEATLARLDLERKIESLE EEIRFLRKIH EEEVRELQEQ LAQQQVHVEM DVAKPDLTAALREIRTQYEA VASSNMHEAE EWYRSKFADL NDAAARNAELLRQAKHEAND YRRQLQALTC DLESLRGTNESLERQMREQE ERHAREAASY QEALARLEEE GQSLKDEMAR HLQEYQDLLN VKLALDIEIA TYRKLLEGEE NRITIPVQTF SNLQIRETSL DTKSVSEGHL KRNIVVKTVE MRDGEVIKESKQEHKDVM\n\nMolecular Weight:\n~49.5kD\n\nApplications:\nSuitable for use in ELISA and Antibody Blocking. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

136900

Size

100ug

Form

Supplied as a liquid.

Purity

Serum

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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