GFI1 (5D7) Antibody

Cat no: 253057

Supplier: ABBIOTEC

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Description
Additional Information

GFI1 (Growth factor independent protein 1) is a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental conte, Xenopus/Amphibian,ts, including hematopoiesis and oncogenesis. It functions as part of a comple, Xenopus/Amphibian, along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. GFl1 is e, Xenopus/Amphibian,pressed in the hematopoietic and lymphoid system, sensory epithelia, lungs and CNS.

Catalogue number:	253057
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q99684
Antigen:	Purified recombinant fragment of human GFI1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	5D7
Additional info:	Zinc finger protein Gfi-1; Growth factor independent protein 1; Zinc finger protein 163; ZNF163; GFI1