GGPS1, Recombinant, Human, His-Tag (Geranylgeranyl Pyrophosphate Synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl Diphosphate Synthase, Dimethylallyltranstransferase, Farnesyl Diphosphate Synthase, Farnesyltranstransferase, Geranylgeranyl Diphosphate S

Supplier:

United States Biological

Cat no: 137989

GGPS1, Recombinant, Human, His-Tag (Geranylgeranyl Pyrophosphate Synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl Diphosphate Synthase, Dimethylallyltranstransferase, Farnesyl Diphosphate Synthase, Farnesyltranstransferase, Geranylgeranyl Diphosphate S

Geranylgeranyl pyrophosphate synthase isoform A, also known as GGPS1, is a member of the prenyltransferase family. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate, a precursor of geranylgeranylated proteins and carotenoids. GGPS1 is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Recombinant human GGPS1 protein, fused to His-tag at N-terminal domain, was expressed in E.coli and purified by using conventional chromatography techniques.\n\nSource:\nRecombinant protein corresponding to aa1-300 from human GGPS1, fused to His-tag at N-terminal domain, expressed in E.coli.\n\nMolecular Weight:\n~37kD (MALDI-TOF)\n\nApplications:\nSuitable for use in SDS-PAGE. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nAA Sequence:\nMGSSHHHHHHSSGLVPRGSHMEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137989

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 10% glycerol.

Purity

~90% (SDS-PAGE)

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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