Home  >  Products  >  GIRK2 (G Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1, Inward Rectifier K(+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)
GIRK2 (G Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1, Inward Rectifier K(+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)

GIRK2 (G Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1, Inward Rectifier K(+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)

Cat no: G2035-05B

Supplier: United States Biological
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GIRK2 is a potassium channel that may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Brain (Substantia Nigra) lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2035-05B
Reactivities: Mouse
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human GIRK2. Species Sequence Homology: canine, mouse and rat

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