Home  >  Products  >  GLI2 (GLI-Kruppel Family Member 2, GLI-Kruppel Family Member GLI2, GLI Family Zinc Finger 2, HPE9, Tax Helper Protein, THP, THP1, THP2, Zinc Finger Protein GLI2)
GLI2 (GLI-Kruppel Family Member 2, GLI-Kruppel Family Member GLI2, GLI Family Zinc Finger 2, HPE9, Tax Helper Protein, THP, THP1, THP2, Zinc Finger Protein GLI2)

GLI2 (GLI-Kruppel Family Member 2, GLI-Kruppel Family Member GLI2, GLI Family Zinc Finger 2, HPE9, Tax Helper Protein, THP, THP1, THP2, Zinc Finger Protein GLI2)

Cat no: G2035-53D

Supplier: United States Biological
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GLI2, also known as GLI-Kruppel family member 2, a 133.3kDa protein belonging to the C2H2-type zinc finger protein subclass of the Gli family of transcription factors. GLI2 and the related GLI3 proteins are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse, GLI2 being primarily a transcriptional activator while GLI3 is a transcriptional repressor. Studies indicate that GLI2 plays a role in embryogenesis. GLI proteins are also implicated as potent oncogenes in the embryonal carcinoma cell. Applications: Suitable for use in ELISA, Immunohistochemistry, and Western Blot. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 5ug/ml. Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. 0.01M sodium citrate buffer, pH 6 is recommended. ELISA: 1:15,000-1:60,000 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher. Positive Control for Immunohistochemistry: Mouse brain Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2035-53D
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: Oncogene GLI2, Tax Helper Protein 1, Tax Helper Protein 2, Tax Responsive Element 2 Holding Protein, Tax Responsive Element-25 bp Sequence Binding Protein
Additional info: Recognizes mouse GLI2. Species Crossreactivity: rat

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