Home  >  Products  >  Gli2 (GLI-Kruppel family member GLI2, THP2, Oncogene GLI2, Tax Helper Protein 2, Tax Responsive Element 2 Holding Protein, Tax Responsive Element-25 bp Sequence Binding Protein, Zinc Finger Protein GLI2)
Gli2 (GLI-Kruppel family member GLI2, THP2, Oncogene GLI2, Tax Helper Protein 2, Tax Responsive Element 2 Holding Protein, Tax Responsive Element-25 bp Sequence Binding Protein, Zinc Finger Protein GLI2)

Gli2 (GLI-Kruppel family member GLI2, THP2, Oncogene GLI2, Tax Helper Protein 2, Tax Responsive Element 2 Holding Protein, Tax Responsive Element-25 bp Sequence Binding Protein, Zinc Finger Protein GLI2)

Cat no: G2035-53B

Supplier: United States Biological
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This protein belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes Greig cephalopolysyndactyly syndrome, Pallister Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. Cellular Localization: Nuclear Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G2035-53B
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ug
Form: 0.01% Sodium Azide; 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: GLI-Kruppel family member GLI2, THP2, Oncogene GLI2, Tax helper protein 2, Tax responsive element 2 holding protein, Tax responsive element-25 bp sequence binding protein, Zinc finger protein GLI2
Additional info: Expected to crossreact with all 4 splice variants of Human Gli as the immunogen sequence is present in all 4. Tested by Western blot on human lung, gives low background, but no band was detected.

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