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Glial Fibrillary Acidic Protein (GFAP, Astrocyte Marker, FLJ45472)

Glial Fibrillary Acidic Protein (GFAP, Astrocyte Marker, FLJ45472)

Cat no: G2037-10G

Supplier: United States Biological
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Glial Fibrillary Acidic Protein (GFAP) is a 50kD intra-cytoplasmic filamentous protein of the cytoskeleton in astrocytes. It has demonstrated to be the most specific marker for cells of astrocytic origin. GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. GFAP immunoreactivity has been shown in immature oligodendrocytes , epiglottic cartilage, pituicytes, papillary meningiomas, myoepithelial cells of the breast and in non-CNS: Schwann cells, salivary gland neoplasms, enteric glia cells and metastasizing renal carcinomas. It
Catalogue number: G2037-10G
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry
Size: 250ug
Form: Supplied as lyophilized powder. Reconstitute with 250ul sterile ddH2O.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Reeves S.A, et al. Proc. Natl. Acad. Sci. U.S.A. 86:5178-5182(1989). 2. Brenner M, et al. Brain Res. Mol. Brain Res. 7:277-286(1990). 2. Isaacs A, et al. Genomics 51:152-154(1998). 3. Ota T, et al. Nat. Genet. 36:40-45(2004). 4. Nielsen A.L, et al. J. Biol. Chem. 277:29983-29991(2002). 5. Singh R, et al. Genomics 82:185-193(2003). 6. Brenner M, et al. Nat. Genet. 27:117-120(2001). 7. Brockmann K, et al. Eur. Neurol. 50:100-105(2003). 8. Stumpf E, et al. Arch. Neurol. 60:1307-1312(2003). 9. Sawaishi Y, et al. Neurology 58:1541-1543(2002). 10. Aoki Y, et al. Neurosci. Lett. 312:71-74(2001).
Additional info: Recognizes rat GFAP. Species Crossreactivity: human, mouse and bovine

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