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Glibenclamide (5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N?-cyclohexylurea)

Glibenclamide (5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N?-cyclohexylurea)

Cat no: G8139-06

Supplier: United States Biological
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Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion. Molecular Weight: ~494 Solubility: DMSO (100mM) or EtOH (5mM) Storage and Stability: May be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

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