GLRA1 Antibody

Cat no: 252031

Supplier: ABBIOTEC

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Description
Additional Information

The glycine receptor (GLAR1) is a neurotransmitter-gated ion channel. Binding of glycine to GLAR1 increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Defects in GLRA1 are a cause of startle disease (STHE), also known as hereditary hyperekple, Xenopus/Amphibian,ia or congenital stiff-person syndrome. STHE is a genetically heterogeneous neurologic disorder characterized by muscular rigidity of central nervous system origin,Porcinearticularly in the neonatal period, and by an e, Xenopus/Amphibian,aggerated startle response to une, Xenopus/Amphibian,pected acoustic or tactile stimuli.

Catalogue number:	252031
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P23415
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GLAR1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Glycine receptor subunit alpha-1; Glycine receptor 48 kDa subunit; Glycine receptor strychnine-binding subunit; GLRA1