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Glucagon (GCG)

Glucagon (GCG)

Cat no: G2040-11F

Supplier: United States Biological
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Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 1-2ug/ml in formalin fixed and paraffin embedded tissues. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS or 1.2% sodium acetate. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G2040-11F
Reactivities: Human, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute with 1ml of sterile PBS or 1.2% sodium acetate
P type: Mab
Isotype: IgG1
Purity: Purified by affinity chromatography.
References: 1. Schroeder, W.T.; Lopez, L.C.: Harper, M.E.; Saunders, G.F.: Localization of the glucagon gene (GCG) to chromosome segment 2q36-37. Cytogenet. cell Genet. 38: 76-79, 1984. 2. White, J.W.; Saunders, G.F.: Structure of the human glucagon gene. Nucleic Acids Res. 14: 4719-4730, 1986.
Additional info: Recognizes Glucagon. Species Crossreactivity: human and rat.

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