| Catalogue number: |
G2040-51B |
| Reactivities: |
Human, Mouse, Rat |
| Hosts: |
Rabbit |
| Applications: |
Immunocytochemistry, Immunohistochemistry, Western Blot |
| Size: |
50ug |
| P type: |
Pab |
| Isotype: |
IgG |
| Purity: |
Purified by immunoaffinity chromatography. |
| Alternative names: |
GCCR, GCR, Glucocorticoid receptor lymphocyte, GR, GRL, Grl1 NR3C1, Nuclear receptor subfamily 3 group C member 1 |
| References: |
This product has been used in:Cidlowski JA et al. Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors. Mol Endocrinol 4:1427-37 (1990). Whitelaw ML et al. Heat shock protein hsp90 regulates dioxin receptor function in vivo. Proc Natl Acad Sci U S A 92:4437-41 (1995). van Steensel B et al. Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus. J Cell Sci 108 (Pt 9):3003-11 (1995). Gaitan D et al. Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer. Mol Endocrinol 9:1193-201 (1995). Whitelaw ML et al. Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation. Mol Cell Biol 14:8343-55 (1994). Trapp T et al. Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13:1457-62 (1994). Bellingham DL et al. Ligand-dependent down-regulation of stably transfected human glucocorticoid receptors is associated with the loss of functional glucocorticoid responsiveness. Mol Endocrinol 6:2090-102 (1992). Rangarajan PN et al. Modulation of glucocorticoid receptor function by protein kinase A. Mol Endocrinol 6:1451-7 (1992). Burnstein KL et al. Autoregulation of glucocorticoid receptor gene expression. Steroids 56:52-8 (1991). McGimsey WC et al. Immunocytochemical localization of the glucocorticoid receptor in rat brain, pituitary, liver, and thymus with two new polyclonal antipeptide antibodies. Endocrinology 129:3064-72 (1991). Burnstein KL et al. Human glucocorticoid receptor cDNA contains sequences sufficient for receptor down-regulation. J Biol Chem 265:7284-91 (1990). |
| Additional info: |
Recognizes Glucocorticoid Receptor at ~97kD from rat liver extract. Species Crossreactivity: Crossreacts with Human, Rat and Mouse. Not yet tested in other species. |
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