Home  >  Products  >  Glucocorticoid Receptor, Phosphorylated (Ser211) (GCCR, GCR, GR, Glucocorticoid Receptor Lymphocyte, GRL, Grl1, Nuclear Receptor Subfamily 3 Group C Member 1, NR3C1)

Glucocorticoid Receptor, Phosphorylated (Ser211) (GCCR, GCR, GR, Glucocorticoid Receptor Lymphocyte, GRL, Grl1, Nuclear Receptor Subfamily 3 Group C Member 1, NR3C1)

Cat no: G2040-51E


Supplier: United States Biological
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Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor. The corresponding gene for the glucocorticoid receptor is NR3C1. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G2040-51E
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.05% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human NR3C1 when phosphorylated at Ser211. Species sequence homology: Mouse.

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