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Glucose-6-Phosphate, Dehydrogenase, G6P-2Na

Cat no: G3053-01C

Glucose-6-Phosphate, Dehydrogenase, G6P-2Na

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. \n\nSodium: 9-15.5% by atomic absorption spectrophotometry \n\nWater: (same/less than) 15% by Karl Fischer \n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. \nSolutions are most stable at pH 2-5.

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SPECIFICATIONS

Catalog Number

G3053-01C

Size

10g

Purity

? 95%. Determined by enzyme analysis with G-6-PDH.\n

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