Home  >  Products  >  Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Member 1, HSP90b1, Stress Inducible Tumor Rejection Antigen gp96, Tumor Rejection Antigen 1, TRA1)
Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Member 1, HSP90b1, Stress Inducible Tumor Rejection Antigen gp96, Tumor Rejection Antigen 1, TRA1)

Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Member 1, HSP90b1, Stress Inducible Tumor Rejection Antigen gp96, Tumor Rejection Antigen 1, TRA1)

Cat no: G3057-40L

Supplier: United States Biological
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Glucose-regulated proteins are a class of proteins which are synthesized in response to glycose deprivation. These proteins, along with the closely related heat shock proteins may be grouped together as a family of stress-response proteins (srp). Elevated levels of srp have been observed in some cancer cells and may be an indication of the biological stresses that influence tumor growth. In a study of 398 breast cancer patients, high levels of each of the srps predicted a shorter desease-free survival in node-negative patients. High levels of srp were also correlated with high levels of cathepsin D, suggesting srp may also increase the metastatic and invasive potential. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.01-0.03ug/ml Optimal dilutions to be determined by the researcher. Positive Control: 3T3 lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G3057-40L
Reactivities: Mouse
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Stojkovic M, Lako M, Stojkovic P, Stewart R, Przyborski S, Armstrong L, Evans J, Herbert M, Hyslop L, Ahmad S, Murdoch A, Strachan T. Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture. Stem Cells. 2004;22(5):790-7. PMID: 15342943.
Additional info: Recognizes mouse TRA1. Species sequence homology: canine and rat.

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